The Palatin Hotel is located near the Old City and within walking distance of some of the city's most famous sites. the Dome of the Rock, the Holy Sepulcher and the Western Wall are all within close proximity of this hotel. Other sites of interest include the Great Synagogue and the Jerusalem Convention Center. The nearest airport from the Palatin Hotel is the Tel Aviv International which is located approximately 17 miles distant.

The Palatin Hotel contains rooms which are universally air-conditioned. Other in-room amenities include satellite television service and private baths equipped with hair dryers.

The Palatin Hotel contains amenities which include a concierge service that can help guests to navigate the city. Tour reservations may also be booked at the hotel. There are also tours available that depart every day from the hotel itself. Every morning, guests are treated to a free Israeli breakfast in the hotel restaurant. E-mail access is provided by the hotel.